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Leveraging clinical and biological insights to drive innovation in psychiatry

See our publications, presentations, and more to discover the revolutionary potential of our precision approach.

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Found 56 Results

May 29, 2025

ALTO-300 as Adjunctive Treatment for Major Depressive Disorder Supported by Mechanistic Validation of Patient Selection Biomarker and Well-Established Safety and Tolerability Profile

April 28, 2025

Gamma Band EEG Sample Entropy, a Patient Selection Biomarker for ALTO-300 in MDD, is Increased by 5-HT2C Agonists in Mice

April 28, 2025

ALTO-203, a Novel Histamine H3 Inverse Agonist, Increase Sucrose Preference in Dopamine-depleted Rats

April 28, 2025

An EEG Biomarker for Predicting Placebo Response in Major Depressive Disorder: Development and Validation Across Open-Label and Double-Blind Trials

April 28, 2025

Translational Utility of ERP and Time-Frequency Features for Cognitive Impairment in Schizophrenia: Preclinical Evaluation of MK-801 Deficits and Rescue by ALTO-101

April 28, 2025

Gamma Band EEG Sample Entropy, a Patient Selection Biomarker for ALTO-300, is Increased by Dopamine Depletion in Humans and Mice

April 28, 2025

Prospective Replication and Application of an EEG-based Placebo Response Prediction Biomarker in Randomized Controlled Trials in Depression

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